Melatonin, in addition to being the primary hormone for normalizing the circadian rhythm (your normal wake and sleep cycle) is also a powerful antioxidant. It quenches free radical production which is responsible for destroying your cells
As we age our melatonin production decreases and if there are chronic disease or inflammatory conditions that will further decrease the melatonin, thus sleeping difficulties.
Two frequently used formulas for sleeping difficulties are Kavinace by Neuroscience and Kavinace Ultra PM also by Neuroscience.
Both formulas contain an ingredient, Phenibut which increase GABA. GABA is an inhibitory neurotransmitter (calming) and plays a key role in the sleep cycle. It’s role is to calm the central nervous system. Low levels of GABA are detected in patients with bipolar and anxiety disorders.
For people who aren’t falling or staying asleep due to “busy brain,” anxiety, etc. Kavinace is a natural, non-addictive consideration..
The other formula Kavinace Ultra PM is designed to promote sleep by promoting healthy levels of the primary neurotransmitters and hormones involved in sleep.
Kavinace Ultra PM combines support for the top 3 calming neurotransmitters and hormones (GABA, serotonin, and melatonin) in one product. The Phenibut acts as a GABA agonist to inhibit the activity of wake centers in the brain. Kavinace Ultra PM also contains Griffonia simplicifolia seed extract which provides 5-HTP. 5-HTP increases serotonin which is a calming neurotransmitter in the brain. The formula also contains Melatonin which promotes sleep through multiple mechanisms!
So the question then is which one to consider? If there are other chronic conditions going on this would indicate a melatonin depletion then you would consider the Kavinace Ultra PM. If you have worked related stress and or anxiety during the day then you would consider the Kavinace.